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Health-Naturale.com
 
Red Wine and Resveratrol: Cup of Good Cheer
Its been proved! A glass of red wine not only keeps you in good
spirits, it also helps you live a longer, healthier life.

Scientists have come closer than ever to solving the mystery of the
French Paradox - why red wine quaffing Mediterraneans live to a
handsome age despite their high-fat diets.

The compound largely responsible for this effect is called Resveratrol
(pronounced rez-VER-a-trawl).

What is Resveratrol?
Resveratrol is a polyphenol compound that has been shown to protect
against cancer, atherosclerosis and other age-related diseases.

It has been identified in more than 70 species of plants, including
mulberries and peanuts. Grapes, however are particularly good sources.
Resveratrol is highly concentrated in the skin of grapes and is abundant
in red wine.

Resveratrol is produced in plants during times of environmental stress
such as adverse weather or insect, animal or pathogenic attack. Stress
on the plant, such as drought or lack of nitrogen, can raise the content
of resveratrol, and this applies to other plants and their polyphenols as
well.

Resveratrol is found in grape skins, from which it is extracted during
the fermentation process. Fresh grape skin contains about 50 to 100
micrograms of resveratrol per gram, while red wine concentrations
range from 1.5 to 3 milligrams per liter.

Resveratrol in Red Wine Extends Lifespan
In a report published online by Nature, lead researcher David A.
Sinclair and colleagues reported, scientists found an ingredient in red
wine that extended the life span of yeast by up to 80 per cent.

Resveratrol seems to mimic the age-enhancing effects of calorie
restriction on the single-celled organism. In this study, the researchers
were surprised to find that yeast cells treated with small doses of
resveratrol lived for an average of 38 generations, compared to 19 for
the untreated yeast. That's the equivalent of a human lifespan of about
200 years!

To match the yeast doses Sinclair claims that humans would need to
drink a glass of red wine morning, noon and night. That might
certainly be agreeable to some people, especially the French.

Resveratrol boosts levels of an enzyme called Sir2, which is thought to
extend lifespan by stabilizing DNA. "It's highly plausible that boosting
enzyme activity will slow functional decline in old age," agrees Peter
Piper, who studies ageing at University College London.

Resveratrol, Saponins, Flavonoids in Red Wine Protect Against Heart
Attack
A glass or two or red wine each day has been shown to lower risk of
heart attack. Much of the credit actually goes to the red pigments in
grape skins, which contain very powerful antioxidants, or flavonoids.

This antioxidant is quercetin, which has been found to be effective in
preventing prostate cancer, relieveing inflammation of the prostate and
joints and a host of other benefits. The tannins in red wine also help
prevent blood platelet cells from clumping together and triggering a
heart attack.

Researchers believe that resveratrol is partially responsible for the
cholesterol-lowering effects of red wine. A team of scientists in China
also found that resveratrol may be at least partly responsible for
improving cardiovascular health.

According to their research, rabbits that drank a little red wine -- with
or without alcohol -- while nibbling on a high-cholesterol diet had
healthier hearts and veins than fellow lab bunnies that drank only
water. And rabbits that drank water mixed with a resveratrol extract
had even better cardiovascular health than the rabbits that drank the
red wine, according to the study, which was conducted at Nanjing
Medical University.

Researchers at Northwestern University Medical School have found that
resveratrol in red wine is a form of estrogen. The estrogenic properties
of resveratrol may play a role in the beneficial cardiovascular effects of
red wine and the so-called 'French paradox,' said researchers.

Estrogen is known to provide some protection against heart disease,
and red wine also appears to. Their specific effects are similar, most
notably, increasing high-density lipoprotein (HDL), the "good
cholesterol." This effect of red wine may be mediated by resveratrol.

Epidemiologic and clinical studies suggest that high consumption of
resveratrol-rich foods may result in reduced cardiovascular disease risk,
lowered total cholesterol, and lowered LDL cholesterol. Resveratrol's
antioxidant properties may again be the mechanism at work in reducing
the oxidation of LDL cholesterol.

Researchers at the university of California, Davis, have identified a new
compound in red wine which could be just as important as resveratrol,
in fighting cholesterol. The scientists said they have found saponins, the
glucose-based plant compounds increasingly under the spotlight for
possible health benefits, in wine for the first time.

Saponins are a hot new food ingredient. No one ever thought to look
for it in wine, said the researchers. The compounds are believed to
come from the waxy skin of grapes, which dissolve into the wine
during its fermentation process.

Red wines contain about the same amount of saponin as they do
resveratrol. But while resveratrol is thought to block cholesterol
oxidation by its antioxidant action, saponins are believed to work by
binding to and preventing the absorption of cholesterol.

Resveratrol in Grapes Fights Cancer
A group of FFH Program scientists led by Dr. John Pezzuto in the
College of Pharmacy at the UIC campus have shown that resveratrol
may prevent cancer.

According to a previous study, an enzyme called CYP1B1, which is
found in tumor cells, metabolizes resveratrol and converts it into
piceatannol, a highly toxic agent that destroys cancer cells.

This process of conversion of resveratrol to piceatannol only seems to
occurs within the tumor, and because the created piceatannol is
localized, it destroys only cancer cells, without harming healthy tissue.

Some researchers have previously suggested that it would be beneficial
to supplement people's diets with resveratrol because of its
anticarcinogenic and anti-arteriosclerotic properties.

One study found that constituents in red wine may be able to reverse
some of the damage caused by cigarettes. The small study found that
red wine, but not its alcohol content, counteracted acute arterial
dysfunction left by cigarettes. The researchers from Alexandra Hospital
in Athens, Greece, reported that a dose of two glasses (250 mL) of red
wine eradicated the harmful effect of one cigarette.

The study shows that red wine contains substances that are powerful
enough to counteract the harmful effect of smoking on arterial function,
which could lead to the discovery of substances capable of reversing
the harmful effects of smoke.

A new project funded by Europeans aims to evaluate the antioxidant
and antiproliferative effects of the metabolites of resveratrol, in the hope
that they could help formulate food additives with antioxidant properties,
which may help reduce mortality from coronary heart disease and
cancer.

------------------------------------------------
Note: If you suffer from platelet deficiency or blood-clotting difficulties
or take blood-thinning drugs like aspirin, you should use resveratrol
supplements only under medical supervision.

--------------------------------------
Longevinex - Red Wine Extract
World's First Stabilized Red Wine Extract. LongevinexTM is the
world's first stabilized red wine extract, providing the healthy properties
of red wine without the alcohol, sulfites, headaches and calories. No
other red wine extract supplement has been found to be biologically
active except LongevinexTM, which is encapsulated in an airtight
capsule to prevent spoilage. One serving of this product (one capsule)
provides no less than 15 milligrams of stabilized Red Wine Polyphenols,
which is equivalent to the amount of active ingredients in 5 to 15
glasses of red wine. Click here to Buy Longevinex
-------------------------
Jarrow Resveratrol Synergy
Jarrow Formulas' Resveratrol Synergy contains the biologically active
flavonoid resveratrol, plus catechins (green tea), anthocyanins (g skin)
and proanthocyanins (OPCs from g seed).

---------------------------
(Âü°í ¹®Çå »ý·«)
 
-------------------------------
These statements have not been evaluated by the FDA.
Health-Naturale.com makes no claim that the products featured are
anything other than dietary supplements designed to improve nutrition
and general well-being. They are not intended to diagnose, cure,
prevent or treat any diseases and do not substitute for a doctor's care
or for proven therapy. The information here is not provided by medical
professionals and is not intended as a substitute for medical advice.
Please consult your physician before beginning any course of treatment.
.........................