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Acupuncture and Transcutaneous Nerve Stimulation in Stroke
Rehabilitation: A Randomized, Controlled Trial. Stroke 2001; 32:707-713.

Effects of Acupuncture Treatment on Daily Life Activities and Quality
of Life: A Controlled, Prospective, and Randomized Study of Acute
Stroke Patients. Stroke 1998; 29:2100-2108.
 
.........................................
Acupuncture and Transcutaneous Nerve Stimulation in Stroke
Rehabilitation, A Randomized, Controlled Trial

Barbro B. Johansson, MD, PhD; Eva Haker, PhD; Magnus von Arbin,
MD, PhD; Mona Britton, MD, PhD; Goran Langstrom, PhD; Andreas
Terent, MD, PhD; Dag Ursing, MD; Kjell Asplund, MD, PhD; for the
Swedish Collaboration on Sensory Stimulation After Stroke1

From the Department of Neurology (B.B.J.), Lund University Hospital,
Lund; Department of Physiotherapy (E.H.), Karolinska Institutet;
Department of Medicine at Danderyd Hospital (M. von A.), Stockholm;
Swedish Council for Technology Assessment in Health Care (M.B.),
Astra Hassle AB (G.L.), Molndal; Departments of Medicine at Uppsala
University Hospital (A.T.), Uppsala; Angelholm Hospital (D.U.),
Angelholm; and Umea University Hospital (K.A.), Umea, Sweden.

Correspondence to Prof Kjell Asplund, Department of Medicine,
University Hospital, SE-901 85 Umea, Sweden.
E-mail kjell.asplund@medicin.umu.se (Stroke 2001: 32-707)

Background and Purpose
In small trials with control groups that receive no intervention,
acupuncture has been reported to improve functional outcome after
stroke. We studied effects of acupuncture and transcutaneous electrical
nerve stimulation on functional outcome and quality of life after stroke
versus a control group that received subliminal electrostimulation.

Methods
In a multicenter randomized controlled trial involving 7 university and
district hospitals in Sweden, 150 patients with moderate or severe
functional impairment were included. At days 5 to 10 after acute stroke,
patients were randomized to 1 of 3 intervention groups: (a) acupuncture,
including electroacupuncture; (b) sensory stimulation with high-intensity,
low-frequency transcutaneous electrical nerve stimulation that induces
muscle contractions; and (c) low-intensity (subliminal) high-frequency
electrostimulation (control group). A total of 20 treatment sessions were
performed over a 10-week period. Outcome variables included motor
function, activities of daily living function, walking ability, social
activities, and life satisfaction at 3-month and 1-year follow-up.

Results
At baseline, patients in each group were closely similar in all important
prognostic variables. At 3-month and 1-year follow-ups, no clinically
important or statistically significant differences were observed between
groups for any of the outcome variables. The 3 treatment modalities
were all conducted without major adverse effects.

Conclusions
When compared with a control group that received subliminal
electrostimulation, treatment during the subacute phase of stroke with
acupuncture or transcutaneous electrical nerve stimulation with muscle
contractions had no beneficial effects on functional outcome or life
satisfaction.

Key Words: acupuncture  trancutaneous electric nerve stimulation 
activities of daily living  quality of life  outcome

..............................
Effects of Acupuncture Treatment on Daily Life Activities and Quality
of Life, A Controlled, Prospective, and Randomized Study of Acute
Stroke Patients
 
Gunilla Gosman-Hedstrom, OT, MSc; Lisbet Claesson, OT, MSc; Ulrika
Klingenstierna, RPT, MSc; Jane Carlsson, RPT, PhD; Bengt Olausson,
MD, PhD; Martin Frizell, MD, PhD; Bjorn Fagerberg, MD, PhD; 
Christian Blomstrand, MD, PhD

From the Department of Clinical Neuroscience, Section of Neurology
(G.G.-H., L.C., J.C., C.B., M.F.), Sahlgrenska University Hospital;
Goteborg College of Health Sciences, Department of Rehabilitation
(G.G.-H., L.C., U.K., J.C.); Department of Clinical Neuroscience, Section
of Psychiatry (B.O.), Molndal/Sahlgrenska University Hospital; and
Department of Medicine, Section of Internal Medicine (B.F.),
Sahlgrenska University Hospital, Goteborg, Sweden.

Correspondence to Associate Professor Christian Blomstrand, Department
of Clinical Neuroscience, Section of Neurology, Sahlgrenska University
Hospital, S-413 45 Goteborg, Sweden. E-mail cbl@neuro.gu.se  (Stroke
1998, 29:2100-2108) 

Background and Purpose
A number of studies have indicated that acupuncture might improve the
functional recovery of stroke patients. These studies vary in inclusion
criteria, sample size, and evaluation methods. The present study was
designed to investigate whether electroacupuncture treatment favorably
affects stroke patients' ability to perform daily life activities, their
health-related quality of life, and their use of health care and social
services.

Methods
One hundred four consecutive patients >40 years of age admitted to
hospital because of an acute stroke were randomized to 3 groups: deep,
superficial, and no acupuncture treatment. The acupuncture treatment
given by 4 physiotherapists started 4 to 10 days after randomization
and was given twice a week for 10 weeks. All patients underwent
conventional stroke rehabilitation as well. Two occupational therapists,
blinded regarding the patients' allocation, evaluated the treatment
effects. The assessments were performed 4 times during the first year
after randomization by means of interviews and observations.

Results
There were no differences between the groups with reference to
changes in the neurological score and the Barthel and Sunnaas activities
of daily living index scores after 3 and 12 months. Regarding the
Nottingham Health Profile, the no acupuncture group had somewhat
fewer mobility problems. No differences in health care and social
services were found between the groups.

Conclusions
The present study does not give support to the previous studies, which
indicates that acupuncture treatment may have a beneficial effect on
acute stroke patients' ability to perform daily life activities, their
health-related quality of life, and their use of health care and social
services.

Key Words: activities of daily living  acupuncture  cerebrovascular
disorders  quality of life  stroke outcome
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